Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731330 | 0.78 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL4543468 | 0.75 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL2347386 | 0.74 | LMNA (0.50) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL358238 | 0.73 | LMNA (0.52) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL7940409 | 0.69 | LMNA (0.61) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL17913870 | 0.69 | LMNA (0.61) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL677098 | 0.69 | LMNA (0.61) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL18395932 | 0.69 | LMNA (0.41) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL24592928 | 0.68 | CYP1A2 (0.41) | LMNAMAPTTSHRALDH1A1CYP1A2 | |
| SCHEMBL11512364 | 0.68 | LMNA (0.65) | LMNAMAPTMAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552080-B2 | Polyurethane foams | RHODIA OPERATIONS (FR) | 2013-10-08 | — | — | US | disclosed |
| US-20110190406-A1 | POLYURETHANE FOAMS | PERFORMANCE POLYAMIDES, SAS (FR) | 2011-08-04 | — | — | US | disclosed |