Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234973 | 0.87 | MAPK1 (0.76) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL531233 | 0.86 | MAPK1 (0.81) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL531700 | 0.85 | MAPK1 (0.62) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL18632010 | 0.84 | GAA (0.75) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL23634710 | 0.83 | HTT (0.50) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL15191149 | 0.83 | MAPK1 (0.79) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL18998183 | 0.82 | AURKB (0.75) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL3655078 | 0.82 | MAPT (0.70) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL30864147 | 0.82 | AURKB (0.75) | MAPK1GAARXFP1NPSR1AURKB | |
| SCHEMBL529439 | 0.82 | MAPK1 (0.77) | MAPK1GAARXFP1NPSR1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139814-A1 | QUINOLINE IMIDAZOLE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |