Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 5/20 | 0.75 |
| ▸ | AURKA | O14965 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18998183 | 1.00 | AURKB (0.75) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL3655078 | 0.91 | MAPT (0.70) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL3787191 | 0.89 | MAPT (0.74) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL403264 | 0.89 | AURKB (0.67) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL402960 | 0.89 | MAPT (0.67) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL529114 | 0.89 | AURKB (0.66) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL22589555 | 0.88 | TP53 (0.73) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL3782311 | 0.88 | GAA (0.67) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL20390760 | 0.88 | AURKB (0.65) | AURKBAURKAMAPK1RXFP1GAA | |
| SCHEMBL23575213 | 0.87 | MAPT (0.81) | AURKBAURKARXFP1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117771374-A | Application of NUDT1 in preparing medicine for treating MYC high expression or MYC amplified tumor | 武汉大学 | 2024-03-29 | — | — | CN | disclosed |