Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 20/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.55 |
| ▸ | MTOR | P42345 | 5/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.52 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634732 | 0.86 | ATM (0.53) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL23634728 | 0.83 | ATM (0.76) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL17245579 | 0.83 | ATM (0.77) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL23634717 | 0.83 | ATM (0.78) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL29705199 | 0.79 | ATM (0.73) | ATMKCNH2PIK3CAATR | |
| SCHEMBL18631938 | 0.79 | ATM (0.73) | ATMKCNH2PIK3CAATR | |
| SCHEMBL17246505 | 0.79 | ATM (0.73) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL18843777 | 0.79 | ATM (0.73) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL20006461 | 0.79 | ATM (0.73) | ATMKCNH2MTORPIK3CAATR | |
| SCHEMBL23634725 | 0.76 | ATM (0.44) | ATMKCNH2MTORPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139814-A1 | QUINOLINE IMIDAZOLE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |