SCHEMBL23634786

SCHEMBL23634786

COc1cc(OC)c(/C=N/N)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
ERN1 O75460 1/20 0.48
CYP1B1 Q16678 5/20 0.47
CYP1A1 P04798 4/20 0.47
CYP1A2 P05177 3/20 0.47
ABCG2 Q9UNQ0 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3833354 0.87 ERN1 (0.64) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL28667568 0.81 LMNA (0.53) LMNAERN1CYP1B1CYP1A1CYP1A2
Methoxymethane SCHEMBL28676370 0.79 LMNA (0.51) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL27090502 0.78 LMNA (0.50) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL18482099 0.78 LMNA (0.50) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL7675590 0.77 GRIN2D (0.65) LMNAERN1CYP1B1CYP1A1GRIN2D
SCHEMBL27644483 0.77 ERN1 (0.52) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL2096170 0.77 ERN1 (0.55) LMNAERN1CYP1B1CYP1A1CYP1A2
SCHEMBL2316541 0.76 GRIN2D (0.64) LMNACYP1B1CYP1A1CYP1A2ALDH1A1
SCHEMBL28737875 0.76 LMNA (0.49) LMNAERN1CYP1B1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210215671-A1 COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS HMI Medical Innovations, LLC 2021-07-15 US disclosed