Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634879 | 0.91 | DDB1 (0.40) | DDB1CRBNIDO1 | |
| SCHEMBL23116689 | 0.85 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL23634846 | 0.84 | DDB1 (0.47) | DDB1CRBNIDO1 | |
| SCHEMBL29322392 | 0.84 | CRBN (0.41) | DDB1CRBNIDO1 | |
| SCHEMBL23634964 | 0.84 | DDB1 (0.47) | DDB1CRBNIDO1 | |
| SCHEMBL23634965 | 0.84 | DDB1 (0.47) | DDB1CRBNIDO1 | |
| SCHEMBL24950356 | 0.84 | CRBN (0.46) | DDB1CRBN | |
| SCHEMBL23634857 | 0.83 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL23634859 | 0.83 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL23634982 | 0.83 | CRBN (0.41) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |