Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158358 | 0.88 | HPGD (0.38) | HPGDKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13202682 | 0.80 | HPGD (0.41) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL1097457 | 0.79 | KMT2A (0.37) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL22845716 | 0.77 | HPGD (0.42) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL20807927 | 0.77 | HPGD (0.39) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL14041545 | 0.77 | HRH3 (0.45) | HPGDHRH3KMT2AMEN1ALDH1A1 | |
| SCHEMBL8159902 | 0.76 | HRH3 (0.52) | HRH3ALDH1A1CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL23871029 | 0.75 | HRH3 (0.36) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL24400561 | 0.74 | HRH3 (0.38) | HPGDHRH3SLC6A4KMT2AMEN1 | |
| SCHEMBL23871026 | 0.74 | HRH3 (0.36) | HPGDHRH3SLC6A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |