Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635250 | 1.00 | CACNA1C (0.48) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL21580502 | 0.94 | CACNA1C (0.49) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL10440528 | 0.89 | CACNA1C (0.51) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL23635213 | 0.88 | CACNA1C (0.48) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL23635224 | 0.88 | CACNA1C (0.48) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL22871641 | 0.88 | CACNA1C (0.51) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL8199354 | 0.88 | CACNA1C (0.51) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL23635230 | 0.87 | CACNA1C (0.46) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL21081293 | 0.85 | CACNA1C (0.43) | CACNA1CPTGS1ESR1PDE4AKDM4E | |
| SCHEMBL21081299 | 0.85 | CACNA1C (0.46) | CACNA1CPTGS1ESR1PDE4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214766-A1 | DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS | NEMIS TECHNOLOGIES AG (CH) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214766-A1 | DIOXETANE COMPOUNDS AND THEIR USE FOR THE DETECTION OF MICROORGANISMS | DAXX, CD14, MYADM | CACNA1C 4455/4885PTGS1 1150/4885ESR1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.