Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20543516 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL20543518 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL21572106 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL23630301 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTHPGDHCAR2 | |
| SCHEMBL9502710 | 0.83 | ALDH1A1 (0.51) | NR1H4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9502712 | 0.83 | ALDH1A1 (0.51) | NR1H4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31384648 | 0.82 | ALDH1A1 (0.50) | NR1H4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31514418 | 0.82 | ALDH1A1 (0.50) | NR1H4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31384696 | 0.81 | NR1H4 (0.49) | NR1H4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13924823 | 0.81 | NR1H4 (0.49) | NR1H4ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |