Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630305 | 0.91 | CNR1 (0.44) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635292 | 0.90 | NPSR1 (0.42) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635402 | 0.90 | DPP4 (0.41) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635298 | 0.87 | HPGD (0.40) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635353 | 0.87 | MET (0.45) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635299 | 0.85 | CNR1 (0.41) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635399 | 0.84 | CNR1 (0.48) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635400 | 0.84 | CNR1 (0.44) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23630453 | 0.83 | HPGD (0.43) | HPGDUSP2POLBALOX12HSD17B10 | |
| SCHEMBL23635363 | 0.80 | HPGD (0.41) | HPGDUSP2POLBALOX12HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |