Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411456 | 0.87 | KDM4E (0.52) | FFAR1GRM5KDM4ELMNACCR1 | |
| SCHEMBL22316415 | 0.87 | TSHR (0.42) | TSHRFFAR1GRM5KDM4ELMNA | |
| SCHEMBL2732615 | 0.82 | TSHR (0.50) | TSHRKDM4ECYP1A2POLBSMN1; SMN2 | |
| SCHEMBL30824691 | 0.81 | KDM4E (0.59) | TSHRGRM5KDM4ELMNACCR1 | |
| SCHEMBL4726132 | 0.81 | KDM4E (0.59) | TSHRGRM5KDM4ELMNACCR1 | |
| Dipyridyl SCHEMBL27792926 | 0.79 | KDM4E (0.64) | FFAR1GRM5KDM4ELMNACCR1 | |
| SCHEMBL21022697 | 0.79 | TSHR (0.65) | TSHRKDM4ELMNACYP1A2L3MBTL1 | |
| SCHEMBL2363578 | 0.78 | NISCH (0.50) | TSHRFFAR1GRM5KDM4ELMNA | |
| SCHEMBL22316416 | 0.77 | NPC1 (0.42) | TSHRFFAR1GRM5KDM4ELMNA | |
| SCHEMBL21022696 | 0.77 | TSHR (0.62) | TSHRKDM4ELMNACYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605460-A | Synthesis of heterocyclic compounds | 普莱希科公司（US） | 2023-01-13 | — | — | CN | disclosed |
| WO-2011101805-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |