SCHEMBL23636149

SCHEMBL23636149

C1=Cc2c(oc3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc23)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.37
PLA2G4A P47712 3/20 0.37
PLA2G10 O15496 1/20 0.35
MAPT P10636 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 2/20 0.33
PRKDC P78527 1/20 0.33
HTT P42858 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
GAA P10253 1/20 0.31
KDM4E B2RXH2 2/20 0.31
NTSR1 P30989 1/20 0.31
CHEK2 O96017 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22195914 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10MAPTMEN1
SCHEMBL24381613 0.91 MEN1 (0.40) PLA2G2APLA2G4APLA2G10MAPTMEN1
SCHEMBL24798763 0.91 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10PRKDCL3MBTL1
SCHEMBL22924259 0.90 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10MAPTMEN1
SCHEMBL25652589 0.89 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10
SCHEMBL21707325 0.89 AHR (0.35) PLA2G2APLA2G4AMAPTMEN1KMT2A
SCHEMBL27390831 0.87 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10
SCHEMBL27351704 0.87 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10MAPTMEN1
SCHEMBL26055226 0.86 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10TSHRPRKDC
SCHEMBL25757776 0.86 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
EP-3356368-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-21 EP disclosed
EP-3150604-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-14 EP disclosed