Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.53 |
| ▸ | ACACB | O00763 | 10/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636913 | 1.00 | RORC (0.53) | RORCACACB | |
| SCHEMBL28582024 | 0.96 | RORC (0.52) | RORCACACB | |
| SCHEMBL28582025 | 0.96 | RORC (0.52) | RORCACACB | |
| SCHEMBL23632744 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632653 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632651 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632785 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632788 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632656 | 0.89 | ACACB (0.53) | ACACB | |
| SCHEMBL23632608 | 0.85 | ACACB (0.52) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |