SCHEMBL23637130

SCHEMBL23637130

C=CCn1c(NC)nc2cc(C(N)=O)cc(OCCCN3CCOCC3)c21

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449010 0.85 STING1 (0.55) STING1
SCHEMBL23637160 0.84 STING1 (0.85) STING1
SCHEMBL26253591 0.84 STING1 (0.57) STING1
SCHEMBL24465500 0.83 STING1 (0.59) STING1
SCHEMBL19451818 0.83 STING1 (0.59) STING1
SCHEMBL19451686 0.81 STING1 (0.90) STING1
SCHEMBL19436532 0.81 STING1 (0.68) STING1
Bromide SCHEMBL23327843 0.80 STING1 (0.67) STING1
Bromide SCHEMBL29619902 0.80 STING1 (0.67) STING1
SCHEMBL24467645 0.79 STING1 (0.95) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed