SCHEMBL19449010

SCHEMBL19449010

C=CCn1c(NC)nc2cc(C(N)=O)cc(OCCCO)c21

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637130 0.85 STING1 (0.60) STING1
SCHEMBL19451486 0.84 STING1 (0.40) STING1
SCHEMBL19436559 0.81 STING1 (0.83) STING1
SCHEMBL22541642 0.81 STING1 (0.62) STING1
SCHEMBL22121353 0.80 STING1 (0.46) STING1
SCHEMBL24467490 0.79 STING1 (0.57) STING1
SCHEMBL22121454 0.79 STING1 (0.60) STING1
SCHEMBL22151614 0.78 STING1 (0.78) STING1
SCHEMBL24467631 0.77 STING1 (0.67) STING1
SCHEMBL24467530 0.76 STING1 (0.94) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440072-B1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-01-29 EP disclosed
WO-2017175156-A1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-10-12 WO disclosed