Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789934 | 0.94 | TSHR (0.41) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL23637198 | 0.80 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL22121045 | 0.80 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL28906815 | 0.78 | PTGER4 (0.45) | TSHRALDH1A1SMN1; SMN2PTGER4MEN1 | |
| SCHEMBL20066428 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2NCOA1NCOA3BPTF | |
| SCHEMBL19451568 | 0.76 | SMN1; SMN2 (0.44) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL28606875 | 0.76 | SMN1; SMN2 (0.44) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL23637187 | 0.76 | AAK1 (0.38) | TSHRALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL22135950 | 0.74 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 | |
| SCHEMBL22121346 | 0.74 | BPTF (0.41) | TSHRALDH1A1SMN1; SMN2NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848366-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |