Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121358 | 0.91 | BPTF (0.40) | SMN1; SMN2ALDH1A1SMPD1PDE4BPDE4A | |
| SCHEMBL20066430 | 0.90 | MAPT (0.40) | SMN1; SMN2ALDH1A1SMPD1PDE4BPDE4A | |
| SCHEMBL22121346 | 0.90 | BPTF (0.41) | SMN1; SMN2ALDH1A1SMPD1PDE4BPDE4A | |
| SCHEMBL19451673 | 0.89 | HTT (0.43) | SMN1; SMN2ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL22121028 | 0.87 | DRD2 (0.43) | SMN1; SMN2ALDH1A1BPTFMAPK1LMNA | |
| SCHEMBL31454620 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1SMPD1PDE4BPDE4A | |
| SCHEMBL23137476 | 0.84 | HTT (0.40) | SMN1; SMN2ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL22150386 | 0.84 | HTT (0.40) | SMN1; SMN2ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL31016393 | 0.84 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1PDE4BPDE4APDE4C | |
| SCHEMBL20066429 | 0.84 | MAPT (0.43) | SMN1; SMN2ALDH1A1SMPD1PDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398225-A1 | PD-L1/STING CONJUGATES AND METHODS OF USE | INCYTE CORPORATION | 2023-12-14 | — | — | US | disclosed |
| US-20180105514-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230398225-A1 | PD-L1/STING CONJUGATES AND METHODS OF USE | STING1, PDCD1LG2, CD274 | SMN1; SMN2 2719/4885ALDH1A1 3719/4885SMPD1 815/4885 |
| US-20180105514-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | RB1, RBBP5, RCC2 | SMN1; SMN2 2058/4885ALDH1A1 3511/4885SMPD1 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.