SCHEMBL23637268

SCHEMBL23637268

N[C@@H]1CCCN(CC(F)(F)F)C1=O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
DPP4 P27487 7/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
PER2 O15055 5/20 0.32
DDR1 Q08345 1/20 0.32
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19170248 1.00 CYP3A4 (0.37) CYP3A4TSHRTDP1MAPTAPEX1
Hydrochloric Acid SCHEMBL19137163 0.98 CYP3A4 (0.36) CYP3A4TSHRTDP1MAPTAPEX1
SCHEMBL15578261 0.89 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPTAPEX1
SCHEMBL15194610 0.89 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPTAPEX1
SCHEMBL19170192 0.89 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPTAPEX1
Hydrochloric Acid SCHEMBL19136827 0.87 CYP3A4 (0.42) CYP3A4TSHRTDP1MAPTAPEX1
Hydrochloric Acid SCHEMBL19136824 0.87 CYP3A4 (0.42) CYP3A4TSHRTDP1MAPTAPEX1
SCHEMBL15621596 0.79 PER2 (0.48) DPP4DPP8DPP7PER2
SCHEMBL9076848 0.79 DPP4 (0.33) DPP4DPP8DPP7PER2ACE
SCHEMBL9076852 0.79 DPP4 (0.33) DPP4DPP8DPP7PER2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3407716-B9 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2021-07-14 EP disclosed