SCHEMBL23637485

SCHEMBL23637485

Clc1cc(C2(c3ccccc3)c3ccccc3-c3ccccc32)cc2c1oc1ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.46
TTR P02766 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
ALOX5 P09917 2/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637442 0.83 AHR (0.40) AHRTTRSMN1; SMN2MEN1KMT2A
SCHEMBL23098725 0.80 TTR (0.41) AHRTTRSMN1; SMN2MEN1KMT2A
SCHEMBL21975156 0.79 MAPT (0.45) AHRTTRSMN1; SMN2MEN1KMT2A
SCHEMBL437591 0.77 ALOX5 (0.50) AHRSMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL440074 0.77 ALOX5 (0.43) AHRSMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL23098721 0.77 AHR (0.46) AHRTTRSMN1; SMN2MEN1KMT2A
SCHEMBL22617674 0.77 AHR (0.40) AHRTTRSMN1; SMN2MEN1KMT2A
SCHEMBL440729 0.76 ALOX5 (0.52) AHRSMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL438617 0.76 ALOX5 (0.49) AHRSMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL21975171 0.76 MEN1 (0.45) AHRTTRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed