SCHEMBL23637486

SCHEMBL23637486

Clc1cc(C2(c3ccccc3)c3ccccc3-c3c2ccc2ccccc32)c2c(c1)oc1ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A1 P04798 2/20 0.33
CYP1A2 P05177 2/20 0.33
FYN P06241 1/20 0.33
MAPK3 P27361 1/20 0.33
PAX8 Q06710 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
DHFR P00374 1/20 0.32
TYMS P04818 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
WEE1 P30291 1/20 0.31
CYP1B1 Q16678 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637451 0.89 AHR (0.42) AHRL3MBTL1MEN1KMT2AKDM4E
SCHEMBL23637361 0.83 PDK2 (0.37) AHRMEN1KMT2AKDM4EWEE1
SCHEMBL20127213 0.77 SLC6A3 (0.42) CYP1A2DHFRTYMSMEN1KMT2A
SCHEMBL24279298 0.77 AHR (0.43) AHRCYP1A2MEN1KMT2AKDM4E
SCHEMBL15676320 0.77 MAPT (0.42) TDP1DHFRTYMSMEN1KMT2A
SCHEMBL29557713 0.77 MAPT (0.42) TDP1DHFRTYMSMEN1KMT2A
SCHEMBL24279300 0.76 PDK2 (0.33) AHRTDP1L3MBTL1CYP1A1CYP1A2
SCHEMBL26574604 0.76 CYP1A2 (0.40) CYP1A1CYP1A2DHFRTYMSKDM4E
SCHEMBL18927392 0.76 AHR (0.33) AHRTDP1L3MBTL1CYP1A1CYP1A2
SCHEMBL21350390 0.76 AHR (0.32) AHRTDP1L3MBTL1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed