SCHEMBL23637490

SCHEMBL23637490

CC1(C)c2ccccc2-c2c1cc(Cl)cc2C1(c2ccccc2)c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDK2 Q15119 7/20 0.36
PGR P06401 3/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
POLB P06746 1/20 0.33
AKR1A1 P14550 1/20 0.32
AKR1B1 P15121 1/20 0.32
DRD1 P21728 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637414 0.87 PDK2 (0.43) PDK2PGR
SCHEMBL23637424 0.84 PDK2 (0.37) PDK2PGR
SCHEMBL23637508 0.84 PGR (0.41) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23637499 0.82 MEN1 (0.39) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23637493 0.80 MEN1 (0.42) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23637502 0.80 MEN1 (0.42) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL24328671 0.78 ESR1 (0.42) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23637495 0.78 MEN1 (0.37) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL29945027 0.78 PDK2 (0.54) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL16871337 0.77 PDK2 (0.57) PDK2PGRDRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed