SCHEMBL23637494

SCHEMBL23637494

Clc1cc(C2(c3ccccc3)c3ccccc3-c3ccccc32)c2c(c1)sc1ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
GPR3 P46089 1/20 0.33
LMNA P02545 1/20 0.33
OPRK1 P41145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHEK1 O14757 1/20 0.32
WEE1 P30291 1/20 0.32
MCL1 Q07820 2/20 0.32
POLB P06746 1/20 0.32
DUSP3 P51452 1/20 0.32
BLM P54132 1/20 0.32
PTPN5 P54829 1/20 0.32
PTPN11 Q06124 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDK2 Q15119 3/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637503 0.83 MAPT (0.37) KDM4EMEN1MAPTKMT2AGPR3
SCHEMBL23637500 0.82 KDM4E (0.35) KDM4EMEN1MAPTKMT2AGPR3
SCHEMBL23637425 0.81 NQO1 (0.34)
SCHEMBL23637402 0.77 ALDH1A1 (0.33) MAPTGPR3SMN1; SMN2POLBTDP1
SCHEMBL23225942 0.76 KDM4E (0.33) KDM4EMEN1MAPTKMT2AGPR3
SCHEMBL23637504 0.74 KDM4E (0.35) KDM4EMEN1MAPTKMT2AMCL1
SCHEMBL27450684 0.74 KDM4E (0.33) KDM4EMEN1MAPTKMT2ALMNA
SCHEMBL23637451 0.74 AHR (0.42) KDM4EMEN1MAPTKMT2ALMNA
SCHEMBL22104846 0.74 MEN1 (0.36) KDM4EMEN1MAPTKMT2AGPR3
SCHEMBL18034440 0.73 KDM4E (0.42) KDM4EMEN1MAPTKMT2AGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed