Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032120 | 0.85 | ALDH1A1 (0.38) | PIM1ALDH1A1HPGDRECQLALOX15 | |
| Triphenylene SCHEMBL29032122 | 0.75 | IDO1 (0.41) | ALDH1A1HPGDRECQLALOX15HSD17B10 | |
| SCHEMBL372102 | 0.75 | PIM1 (0.43) | PIM1ALDH1A1HPGDRECQLALOX15 | |
| SCHEMBL29032121 | 0.71 | SRC (0.40) | PIM1ALDH1A1HPGDRECQLALOX15 | |
| SCHEMBL5949024 | 0.69 | — | — | |
| SCHEMBL29986805 | 0.68 | PADI4 (0.44) | ALDH1A1HPGDRECQLHSD17B10MAPT | |
| SCHEMBL2935017 | 0.68 | ALDH1A1 (0.62) | ALDH1A1HPGDRECQLALOX15HSD17B10 | |
| SCHEMBL1502477 | 0.68 | PADI4 (0.44) | ALDH1A1HPGDRECQLHSD17B10MAPT | |
| SCHEMBL31035972 | 0.68 | ALDH1A1 (0.62) | ALDH1A1HPGDRECQLALOX15HSD17B10 | |
| SCHEMBL5981701 | 0.68 | HSD17B10 (0.43) | ALDH1A1HPGDRECQLALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142474-A1 | COVALENT ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-15 | — | — | WO | disclosed |