SCHEMBL23638211

SCHEMBL23638211

CCNCN1CCCCC1COc1cccc(NS(N)(=O)=O)c1C#N

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRAF P15056 2/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
CHRNB3 Q05901 1/20 0.32
FAAH O00519 2/20 0.31
CHRM3 P20309 1/20 0.31
DRD2 P14416 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15567768 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL28362245 0.80 ALDH1A1 (0.38) ALDH1A1
SCHEMBL15568054 0.78 IRAK4 (0.41) ALDH1A1
SCHEMBL15568053 0.78 IRAK4 (0.41) ALDH1A1
SCHEMBL18224085 0.78 F2RL3 (0.40) ALDH1A1
SCHEMBL15607442 0.78 F2RL3 (0.40) ALDH1A1
SCHEMBL2415041 0.76 MCHR1 (0.41)
SCHEMBL2414259 0.76 MRGPRX1 (0.43) BRAF
SCHEMBL2413234 0.74 PTGES2 (0.42) BRAFALDH1A1
SCHEMBL15607210 0.73 HRH3 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3593648-B1 SWEET FLAVOR MODIFIER FIRMENICH INCORPORATED (US) 2021-07-14 EP disclosed