Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838038 | 1.00 | USP2 (0.36) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL23638379 | 0.87 | NPC1 (0.38) | USP2MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23638477 | 0.80 | IRAK4 (0.33) | USP2SMN1; SMN2ALDH1A1LGALS8 | |
| SCHEMBL15111825 | 0.73 | MCHR1 (0.46) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL29837918 | 0.72 | MAPT (0.45) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL17673627 | 0.72 | MAPT (0.45) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL31473684 | 0.71 | MAPT (0.46) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL15111868 | 0.71 | MAPT (0.46) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL31588703 | 0.71 | MAPT (0.46) | USP2MAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL17678216 | 0.71 | MAPT (0.42) | USP2MAPTMAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901664-B | Pyridone compounds and uses thereof | 南京再明医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114901664-A | Pyridone compound and application thereof | 江苏先声药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |