Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638463 | 0.83 | IRAK4 (0.39) | IRAK4ALDH1A1USP2SMN1; SMN2IDO1 | |
| SCHEMBL23638379 | 0.81 | NPC1 (0.38) | ALDH1A1USP2SMN1; SMN2LGALS8 | |
| SCHEMBL29838038 | 0.80 | USP2 (0.36) | ALDH1A1USP2SMN1; SMN2LGALS8 | |
| SCHEMBL23638478 | 0.80 | USP2 (0.36) | ALDH1A1USP2SMN1; SMN2LGALS8 | |
| SCHEMBL17678259 | 0.76 | IRAK4 (0.38) | IRAK4IDO1TDO2 | |
| SCHEMBL23638264 | 0.76 | IRAK4 (0.40) | IRAK4ALDH1A1LGALS8IDO1TDO2 | |
| SCHEMBL29837912 | 0.74 | L3MBTL1 (0.40) | IRAK4ALDH1A1SMN1; SMN2LGALS8IDO1 | |
| SCHEMBL28807179 | 0.74 | L3MBTL1 (0.40) | IRAK4ALDH1A1SMN1; SMN2LGALS8IDO1 | |
| SCHEMBL23638468 | 0.74 | IRAK4 (0.39) | IRAK4LGALS8IDO1TDO2ROCK1 | |
| SCHEMBL17678163 | 0.74 | POLB (0.44) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901664-A | Pyridone compound and application thereof | 江苏先声药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |