Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 4/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807176 | 1.00 | IDO1 (0.33) | IDO1TDO2SIGMAR1KDM4ELMNA | |
| SCHEMBL28807184 | 0.84 | HDAC3 (0.44) | IDO1TDO2LMNAMCHR1HDAC3 | |
| SCHEMBL31394882 | 0.81 | LPL (0.43) | IDO1TDO2LPLLIPGFFAR1 | |
| SCHEMBL23638277 | 0.79 | KMT2A (0.43) | SIGMAR1KDM4ELMNAKCNH2MCHR1 | |
| SCHEMBL23638383 | 0.79 | KMT2A (0.43) | SIGMAR1KDM4ELMNAKCNH2MCHR1 | |
| SCHEMBL23638441 | 0.79 | FFAR1 (0.39) | IDO1TDO2LPLLIPGFFAR1 | |
| SCHEMBL23638498 | 0.78 | KDM4E (0.42) | SIGMAR1KDM4ELMNAKCNH2MCHR1 | |
| SCHEMBL23632999 | 0.78 | KDM4E (0.42) | SIGMAR1KDM4ELMNAKCNH2MCHR1 | |
| SCHEMBL23638437 | 0.78 | IDO1 (0.37) | IDO1TDO2LPLLIPGFFAR1 | |
| SCHEMBL17113584 | 0.78 | LPL (0.41) | IDO1TDO2LPLLIPGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |