SCHEMBL23639129

SCHEMBL23639129

Clc1cccc2c(-c3ccccc3)c(I)c3ccccc3c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2 P11137 1/20 0.38
CYP2A6 P11509 4/20 0.37
CYP1A2 P05177 4/20 0.37
DYRK1A Q13627 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
FABP3 P05413 2/20 0.33
FABP4 P15090 2/20 0.33
CNR1 P21554 1/20 0.33
FABP5 Q01469 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ACHE P22303 1/20 0.32
ENPP1 P22413 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28391800 0.81 CYP1A2 (0.46) MAP2CYP2A6CYP1A2DYRK1AESR1
SCHEMBL13016368 0.79 ENPP1 (0.36) CYP2A6CYP1A2ESR1ESR2CYP3A4
SCHEMBL29367682 0.77 CYP1A2 (0.42) MAP2CYP2A6CYP1A2DYRK1AESR1
SCHEMBL1758344 0.77 CYP1A2 (0.42) MAP2CYP2A6CYP1A2DYRK1AESR1
SCHEMBL13016375 0.76 ESR1 (0.45) ESR1ESR2ACHEKDM4EMAPT
SCHEMBL22717148 0.76 ESR1 (0.48) ESR1ESR2ACHEKDM4EMAPT
SCHEMBL10431739 0.73 CYP1A2 (0.58) CYP2A6CYP1A2DYRK1AGABRPGABRD
SCHEMBL17614919 0.73 ESR1 (0.36) CYP1A2ESR1ESR2CYP3A4CYP2C9
SCHEMBL23639132 0.72 ALDH1A1 (0.43) CYP2A6CYP1A2CYP3A4KDM4EMAPT
SCHEMBL23639144 0.71 DPP4 (0.43) MAP2DYRK1AESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139452-A1 ORGANIC ELECTRONIC MATERIAL CONTAINING NITROGEN ATOM HETEROCYCLIC RING, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海传勤新材料有限公司 2021-07-15 WO disclosed