Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064836 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1GAAKMT2ASTAT3RECQL | |
| SCHEMBL13433912 | 0.86 | KMT2A (0.40) | ALDH1A1GAAKMT2ACA1CA2 | |
| SCHEMBL7265141 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1GAAKMT2ASTAT3RECQL | |
| SCHEMBL1990107 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1GAAKMT2ASTAT3RECQL | |
| SCHEMBL2328955 | 0.84 | KMT2A (0.46) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL17789129 | 0.83 | KMT2A (0.44) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL2326857 | 0.83 | KMT2A (0.44) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL31712160 | 0.83 | KMT2A (0.44) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL10807956 | 0.82 | KMT2A (0.38) | ALDH1A1GAAKMT2ACA12CA2 | |
| SCHEMBL3482877 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806339-B1 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB PHARMA SA (BE) | 2011-08-17 | — | — | EP | disclosed |