Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659887 | 0.93 | MAP3K7 (0.85) | MAP3K7TAB1 | |
| SCHEMBL660615 | 0.89 | MAP3K7 (0.70) | MAP3K7TAB1 | |
| SCHEMBL659132 | 0.87 | MAP3K7 (0.64) | MAP3K7TAB1 | |
| SCHEMBL659133 | 0.87 | MAP3K7 (0.64) | MAP3K7TAB1 | |
| SCHEMBL658409 | 0.85 | MAP3K7 (0.74) | MAP3K7TAB1 | |
| SCHEMBL660273 | 0.85 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| Hydrochloric Acid SCHEMBL659188 | 0.84 | MAP3K7 (0.73) | MAP3K7TAB1 | |
| SCHEMBL2331926 | 0.82 | MAP3K7 (0.65) | MAP3K7TAB1 | |
| SCHEMBL659032 | 0.81 | MAP4K3 (0.74) | MAP3K7TAB1 | |
| SCHEMBL657459 | 0.80 | MAP3K7 (1.00) | MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |