Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 20/20 | 0.65 |
| ▸ | TAB1 | Q15750 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657146 | 0.91 | MAP3K7 (0.76) | MAP3K7TAB1 | |
| SCHEMBL659878 | 0.87 | MAP3K7 (0.61) | MAP3K7TAB1 | |
| SCHEMBL2363983 | 0.82 | MAP3K7 (0.74) | MAP3K7TAB1 | |
| SCHEMBL2331535 | 0.80 | MAP3K7 (0.59) | MAP3K7TAB1 | |
| SCHEMBL657459 | 0.79 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL657222 | 0.79 | MAP3K7 (0.59) | MAP3K7TAB1 | |
| SCHEMBL14693514 | 0.79 | MAP3K7 (0.87) | MAP3K7TAB1 | |
| SCHEMBL659404 | 0.78 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL10217685 | 0.77 | MAP3K7 (0.77) | MAP3K7TAB1 | |
| SCHEMBL659608 | 0.77 | MAP3K7 (1.00) | MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |