Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.58 |
| ▸ | PPARD | Q03181 | 7/20 | 0.58 |
| ▸ | PPARA | Q07869 | 7/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL21815756 | 0.96 | FFAR3 (0.69) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL11514681 | 0.93 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butane SCHEMBL12987048 | 0.90 | FFAR3 (0.61) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL21518139 | 0.90 | SLC22A6 (0.69) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL992031 | 0.89 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1402173 | 0.89 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL30439824 | 0.89 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28781421 | 0.89 | FFAR3 (0.93) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28184121 | 0.88 | LMNA (0.75) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28142253 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107541122-B | A kind of solvent type PVDF coating | 乳源东阳光氟树脂有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-110225742-A | transparent solid cosmetic | 高级醇工业株式会社 | 2019-09-10 | — | — | CN | claimed |
| CN-109528542-A | A kind of composition and preparation method thereof based on private gene customization cell repair | 广州科恩生物技术有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-109528587-A | One kind is based on private gene customization cleawhite over-night essences and preparation method thereof | 广州科恩生物技术有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-107541122-A | A kind of solvent-borne type PVDF coating | 乳源东阳光氟树脂有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-107433109-A | A kind of preparation method for the compound adsorbent for effectively removing carbon dioxide | 东莞市联洲知识产权运营管理有限公司 | 2017-12-05 | — | — | CN | claimed |
| CN-106876003-A | Match solar battery front side conductive silver paste and preparation method without net netting version | 江苏欧耐尔新型材料股份有限公司 | 2017-06-20 | — | — | CN | claimed |
| US-20100076161-A1 | Manufacturing Method of Polyaspartic Acid Using Maleic Anhydride | AEKYUNG PETROCHEMICAL CO., LTD. (KR) | 2010-03-25 | — | — | US | claimed |
| WO-2008038874-A1 | MANUFACTURING METHOD OF POLYASPARTIC ACID USING MALEIC ANHYDRIDE | AEKYUNG PETROCHEMICAL CO., LTD. (KR) | 2008-04-03 | — | — | WO | claimed |
| EP-4745198-A1 | RESIN COMPOSITION, MOLDED ARTICLE, RESIN ADDITIVE COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, METHOD FOR IMPROVING CRYSTALLINITY OF CRYSTALLINE RESIN, AND MATERIAL FOR RESIN ADDITIVE COMPOSITION | ADEKA CORPORATION (JP) | 2026-05-20 | — | — | EP | disclosed |
| US-20260022204-A1 | ANTISTATIC AGENT, ANTISTATIC AGENT COMPOSITION CONTAINING SAME, ANTISTATIC RESIN COMPOSITION CONTAINING SAID ANTISTATIC AGENT OR SAID ANTISTATIC AGENT COMPOSITION, AND MOLDED BODY AND FILM THEREOF | ADEKA CORPORATION (JP) | 2026-01-22 | — | — | US | disclosed |
| US-12466938-B2 | Resin additive composition, thermoplastic resin composition, and molded article thereof | ADEKA CORPORATION (JP) | 2025-11-11 | — | — | US | disclosed |
| EP-4582507-A1 | ANTISTATIC AGENT, ANTISTATIC AGENT COMPOSITION CONTAINING SAME, ANTISTATIC RESIN COMPOSITION CONTAINING SAID ANTISTATIC AGENT OR SAID ANTISTATIC AGENT COMPOSITION, AND MOLDED BODY AND FILM THEREOF | ADEKA CORPORATION (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-120035613-A | Acetals of ethylene vinyl alcohol copolymers, compositions and barrier materials comprising the acetals | 株式会社可乐丽 | 2025-05-23 | — | — | CN | disclosed |
| EP-0218245-A2 | Injection stretch blow container | KURARAY CO., LTD. (JP) | 1987-04-15 | — | — | EP | disclosed |
| US-4613644-A | HYDROLYZED ETHYLENE-VINYL ACETATE COPOLYMER, THERMOPLASTIC RESIN, OXIDE OR FATTY ACID SALT, MOLDING MATERIALS, GAS BARRIERS | KURARAY CO., LTD. (JP) | 1986-09-23 | — | — | US | disclosed |
| US-4613527-A | PUR-coating compositions which are cross-linkable under heat, a process for their production and their use thereof as an adhesive coat for textiles | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4574147-A | Process for the production of polyurethanes, polyurethanes containing terminal aromatic amino groups and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-04 | — | — | US | disclosed |
| EP-0165383-A2 | Resinous composition | KURARAY CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |
| US-4085165-A | ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT | BRIDGESTONE TIRE CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022204-A1 | ANTISTATIC AGENT, ANTISTATIC AGENT COMPOSITION CONTAINING SAME, ANTISTATIC RESIN COMPOSITION CONTAINING SAID ANTISTATIC AGENT OR SAID ANTISTATIC AGENT COMPOSITION, AND MOLDED BODY AND FILM THEREOF | PHOSPHO1, EBP, CA1 | FFAR3 979/4885HDAC3 3171/4885HDAC1 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.