Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456015 | 0.87 | CA12 (0.52) | CYP19A1CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL5979768 | 0.86 | CYP11B1 (0.62) | CYP19A1CYP11B1CYP11B2CA1CA2 | |
| SCHEMBL14156999 | 0.84 | MAPT (0.44) | CYP19A1CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL3019686 | 0.83 | NCEH1 (0.58) | CYP19A1CYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL3010069 | 0.82 | CYP11B1 (0.65) | CYP19A1CYP11B1CYP11B2CYP1A2CYP2A6 | |
| SCHEMBL31553099 | 0.82 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL14279013 | 0.81 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2CA1CA2 | |
| SCHEMBL8557380 | 0.80 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL1359473 | 0.80 | ESR1 (0.53) | CYP1A2CYP2A6TUBB4ATUBBTUBA3C | |
| SCHEMBL23060791 | 0.80 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |