Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28862956 | 0.86 | RXFP1 (0.44) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL3829305 | 0.85 | MAPT (0.55) | NCEH1RXFP1POLBLMNASMN1; SMN2 | |
| SCHEMBL30638066 | 0.85 | MAPT (0.55) | NCEH1RXFP1POLBLMNASMN1; SMN2 | |
| SCHEMBL31553099 | 0.84 | CYP19A1 (0.51) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL23640316 | 0.83 | CYP19A1 (0.52) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL14279013 | 0.83 | CYP19A1 (0.52) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL5752998 | 0.83 | POLB (0.55) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL5749500 | 0.83 | IDO1 (0.57) | NCEH1RXFP1POLBLMNASMN1; SMN2 | |
| SCHEMBL8557380 | 0.81 | CYP19A1 (0.51) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 | |
| SCHEMBL3160115 | 0.81 | POLB (0.50) | NCEH1CYP19A1CYP11B1CYP11B2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840996-A | Production of brominated methoxynaphthalene compounds | ALBEMARLE CORPORATION (US) | 1998-11-24 | — | — | US | claimed |
| WO-1998050334-A1 | PRODUCTION OF BROMINATED METHOXYNAPHTHALENE COMPOUNDS | ALBEMARLE CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| EP-0179447-B1 | PROCESS FOR THE SYNTHESIS OF 2-METHOXY-6-BROMO-NAPHTHALENE | Montedison S.p.A. (IT) | 1989-07-19 | — | — | EP | claimed |
| US-4628123-A | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | MONTEDISON S.P.A. (IT) | 1986-12-09 | — | — | US | claimed |
| EP-0179447-A1 | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | Montedison S.p.A. (IT) | 1986-04-30 | — | — | EP | claimed |
| CN-115197042-A | Deuterated dinaphthyl anthracene compound and preparation method and application thereof | 上海传勤新材料有限公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-1853261-B1 | SELECTIVE INHIBITORS OF HUMAN CORTICOSTEROID SYNTHASES | UNIV SAARLAND (DE) | 2017-01-11 | — | — | EP | disclosed |
| US-9271963-B2 | Selective inhibitors of human corticosteroid synthases | UNIVERSITAT DES SAARLANDES (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9271963-B2 | Selective inhibitors of human corticosteroid synthases | UNIVERSITAT DES SAARLANDES (DE) | 2016-03-01 | — | — | US | disclosed |
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| CN-104418716-A | Preparation method of nabumetone intermediate 2-methoxyl-6-naphthaldehyde | FUJIAN LIFEIKE BIOTECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| WO-1998050334-A1 | PRODUCTION OF BROMINATED METHOXYNAPHTHALENE COMPOUNDS | ALBEMARLE CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050334-A1 | PRODUCTION OF BROMINATED METHOXYNAPHTHALENE COMPOUNDS | ALBEMARLE CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5243088-A | 1-MONODEBROMINATION OF DIBROMONAPHTHALENE COMPOUNDS | POTASSE ET PRODUITS CHIMIQUES (FR) | 1993-09-07 | — | — | US | disclosed |
| EP-0179447-B1 | PROCESS FOR THE SYNTHESIS OF 2-METHOXY-6-BROMO-NAPHTHALENE | Montedison S.p.A. (IT) | 1989-07-19 | — | — | EP | disclosed |
| US-4628123-A | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | MONTEDISON S.P.A. (IT) | 1986-12-09 | — | — | US | disclosed |
| US-4628123-A | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | MONTEDISON S.P.A. (IT) | 1986-12-09 | — | — | US | disclosed |
| EP-0179447-A1 | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | Montedison S.p.A. (IT) | 1986-04-30 | — | — | EP | disclosed |
| EP-0179447-A1 | Process for the synthesis of 2-methoxy-6-bromo-naphthalene | Montedison S.p.A. (IT) | 1986-04-30 | — | — | EP | disclosed |