⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273361 | 0.73 | — | — | |
| SCHEMBL13956997 | 0.73 | — | — | |
| SCHEMBL24302268 | 0.73 | — | — | |
| SCHEMBL23640229 | 0.73 | — | — | |
| SCHEMBL23640517 | 0.67 | TAAR1 (0.33) | — | |
| SCHEMBL13148713 | 0.67 | — | — | |
| SCHEMBL23640038 | 0.65 | — | — | |
| SCHEMBL11928895 | 0.65 | — | — | |
| SCHEMBL24302595 | 0.65 | — | — | |
| SCHEMBL11928891 | 0.64 | HRH3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |