SCHEMBL23640517

SCHEMBL23640517

CNCCC1=CC(C)C(C)C=C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.33
ATM Q13315 1/20 0.33
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13956997 0.70
SCHEMBL23640229 0.70
SCHEMBL14273361 0.70
SCHEMBL24302268 0.70
SCHEMBL24302261 0.68 HTR1B (0.39)
SCHEMBL23640163 0.68 HTR1B (0.39)
SCHEMBL23640326 0.67
SCHEMBL24303010 0.66 L3MBTL1 (0.41)
SCHEMBL23640528 0.66 L3MBTL1 (0.41)
SCHEMBL21396214 0.64 ATM (0.31) TAAR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848367-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-07-14 EP disclosed