Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.72 |
| ▸ | ADH1A | P07327 | 4/20 | 0.72 |
| ▸ | ADH7 | P40394 | 4/20 | 0.72 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.72 |
| ▸ | ADH1C | P00326 | 3/20 | 0.72 |
| ▸ | ADH4 | P08319 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640543 | 0.98 | ADH1B (0.69) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL23640389 | 0.98 | EPHX1 (0.75) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL23640595 | 0.96 | EPHX1 (0.72) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL8043725 | 0.96 | EPHX1 (0.72) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL19996858 | 0.94 | ADH1B (0.63) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL19415950 | 0.90 | ADH1B (0.61) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL9658779 | 0.85 | EPHX1 (1.00) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL305123 | 0.85 | EPHX1 (1.00) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL4879688 | 0.85 | EPHX1 (1.00) | ADH1BADH1AADH7EPHX1ADH1C | |
| SCHEMBL9661679 | 0.85 | EPHX1 (1.00) | ADH1BADH1AADH7EPHX1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NCOA1, NCOR1, NCOA3 | ADH1B 3100/4885ADH1A 2575/4885ADH7 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.