Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26712212 | 1.00 | GAA (0.32) | GAAMGAM | |
| SCHEMBL26058831 | 1.00 | GAA (0.32) | GAAMGAM | |
| SCHEMBL26058826 | 1.00 | GAA (0.32) | GAAMGAM | |
| SCHEMBL24579175 | 0.84 | GAA (0.32) | GAAMGAM | |
| SCHEMBL18287735 | 0.81 | — | — | |
| SCHEMBL25999270 | 0.79 | — | — | |
| SCHEMBL26004530 | 0.79 | — | — | |
| SCHEMBL26267486 | 0.79 | — | — | |
| SCHEMBL26267485 | 0.79 | — | — | |
| SCHEMBL23206546 | 0.79 | GAA (0.35) | GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139678-A1 | PYRIDOPYRIMIDINE KRAS G12C MUTANT PROTEIN INHIBITOR | 广州百霆医药科技有限公司 | 2021-07-15 | — | — | WO | disclosed |