⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26267485 | 1.00 | — | — | |
| SCHEMBL26004530 | 1.00 | — | — | |
| SCHEMBL25999270 | 1.00 | — | — | |
| SCHEMBL29306618 | 0.85 | — | — | |
| SCHEMBL29295924 | 0.81 | — | — | |
| SCHEMBL14626886 | 0.81 | — | — | |
| SCHEMBL29295947 | 0.80 | ALDH1A1 (0.30) | — | |
| SCHEMBL24649127 | 0.79 | — | — | |
| SCHEMBL22349100 | 0.79 | DPP4 (0.31) | — | |
| SCHEMBL22062764 | 0.79 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228511-A1 | SUBSTITUTED FUSED AZINES AS KRAS G12D INHIBITORS | ELI LILLY AND COMPANY | 2024-07-11 | — | — | US | disclosed |
| US-20240228511-A1 | SUBSTITUTED FUSED AZINES AS KRAS G12D INHIBITORS | ELI LILLY AND COMPANY | 2024-07-11 | — | — | US | disclosed |
| US-11760744-B2 | Fused ring compounds | GENENTECH, INC. (US) | 2023-09-19 | — | — | US | disclosed |