Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959831 | 0.93 | CYP11B1 (0.42) | CYP11B1RAB9ANPC1LMNAMAPT | |
| SCHEMBL1959006 | 0.93 | RAB9A (0.40) | CYP11B1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL2351143 | 0.83 | ADORA2A (0.45) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL1959850 | 0.83 | AHR (0.43) | CYP11B1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL1958995 | 0.81 | HDAC1 (0.38) | CYP11B1SMN1; SMN2NPC1LMNACYP11B2 | |
| SCHEMBL1960628 | 0.80 | CYP11B1 (0.37) | CYP11B1SMN1; SMN2LMNAMAPTCYP11B2 | |
| SCHEMBL1961364 | 0.79 | HDAC1 (0.42) | SMN1; SMN2LMNAHDAC1HDAC6KMT2A | |
| SCHEMBL2347180 | 0.79 | SMN1; SMN2 (0.37) | CYP11B1SMN1; SMN2CYP11B2HDAC1HDAC6 | |
| SCHEMBL1961666 | 0.79 | NR1H2 (0.46) | LMNAMAPTHDAC1HDAC6MAPK1 | |
| SCHEMBL1958857 | 0.79 | AHR (0.42) | CYP11B1RAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521754-B1 | VIRAL INHIBITORS | LEUVEN K U RES & DEV (BE) | 2011-08-31 | — | — | EP | claimed |