SCHEMBL23640965

SCHEMBL23640965

CC=C=CC1NCc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
CYP2D6 P10635 3/20 0.33
CYP3A4 P08684 2/20 0.33
PRCP P42785 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD1 P21728 4/20 0.33
DRD2 P14416 3/20 0.33
DRD4 P21917 3/20 0.33
TP53 P04637 2/20 0.33
CYP1A2 P05177 2/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30827216 0.77 CYP2D6 (0.40) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL13662985 0.77 CYP2D6 (0.38) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL3087062 0.73 CYP2D6 (0.38) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL30435099 0.73 CYP2D6 (0.38) ALDH1A1MAPTCYP2D6CYP3A4PRCP
Trimethylammonium SCHEMBL28784704 0.71 ALDH1A1 (0.36) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL29858101 0.66 ALDH1A1 (0.47) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL873420 0.66 ALDH1A1 (0.47) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL9851308 0.66 ALDH1A1 (0.47) ALDH1A1MAPTCYP2D6CYP3A4PRCP
SCHEMBL13302986 0.66 ALDH1A1 (0.47) ALDH1A1MAPTCYP2D6CYP3A4PRCP
Hydrochloric Acid SCHEMBL17671007 0.65 MAPT (0.50) ALDH1A1MAPTCYP2D6CYP3A4PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663308-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-07-14 EP disclosed