SCHEMBL23640978

SCHEMBL23640978

OCc1cc(OCc2ccccc2)c(Br)cc1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.53
F2 P00734 1/20 0.53
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CTSG P08311 1/20 0.48
USP28 Q96RU2 1/20 0.47
USP25 Q9UHP3 1/20 0.47
HTT P42858 1/20 0.46
CCR5 P51681 1/20 0.44
RHEB Q15382 1/20 0.44
PTGER1 P34995 1/20 0.44
HTR1A P08908 1/20 0.44
DRD2 P14416 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539239 0.94 ELANE (0.50) ELANEF2RAB9ASMN1; SMN2CTSG
SCHEMBL31611455 0.88 RAB9A (0.48) ELANEF2RAB9ASMN1; SMN2USP28
SCHEMBL22918092 0.86 ELANE (0.47) ELANEF2RAB9ASMN1; SMN2CTSG
SCHEMBL28441702 0.83 RAB9A (0.47) ELANEF2RAB9ASMN1; SMN2USP28
SCHEMBL1977418 0.83 ELANE (0.47) ELANEF2RAB9ASMN1; SMN2CTSG
SCHEMBL2391164 0.82 SMN1; SMN2 (0.51) RAB9ASMN1; SMN2USP28USP25HTT
SCHEMBL30296039 0.82 SMN1; SMN2 (0.51) RAB9ASMN1; SMN2USP28USP25HTT
SCHEMBL23094689 0.82 KMT2A (0.60) ELANERAB9ASMN1; SMN2CTSGHTT
SCHEMBL18423751 0.82 KMT2A (0.60) ELANERAB9ASMN1; SMN2CTSGHTT
SCHEMBL13991640 0.81 FOLH1 (0.53) ELANEF2CTSGPTGER1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-20210214299-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214299-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME SKP1, PKN1, KTN1 ELANE 4055/4885F2 754/4885RAB9A 3074/4885
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same SKP1, PKN1, KTN1 ELANE 4055/4885F2 754/4885RAB9A 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.