Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299102 | 0.81 | PPARG (0.46) | — | |
| SCHEMBL22299211 | 0.81 | PPARG (0.46) | — | |
| SCHEMBL8594366 | 0.79 | POLB (0.51) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL9721042 | 0.79 | KMT2A (0.62) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL10436144 | 0.78 | CYP1A2 (0.49) | POLBKMT2A | |
| SCHEMBL10336405 | 0.77 | POLB (0.50) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL9721019 | 0.77 | KMT2A (0.60) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL2679457 | 0.77 | KMT2A (0.60) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL9721038 | 0.77 | KMT2A (0.60) | POLBKMT2AMAPTPKMKDM4E | |
| SCHEMBL2947741 | 0.77 | KMT2A (0.60) | POLBKMT2AMAPTPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348855-A2 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | Burnham Institute for Medical Research (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033643-A2 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-03-25 | — | — | WO | disclosed |