Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21415901 | 0.82 | SLC6A4 (0.40) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL20459563 | 0.78 | MAPK1 (0.41) | — | |
| SCHEMBL6877320 | 0.78 | TACR1 (0.47) | TAS1R3TAS1R1TACR1 | |
| SCHEMBL24032728 | 0.73 | SLC6A4 (0.44) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL23642432 | 0.72 | SLC6A4 (0.41) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL21570469 | 0.72 | SLC6A4 (0.34) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL21570467 | 0.72 | SLC6A4 (0.34) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL21570471 | 0.72 | SLC6A4 (0.34) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL17710306 | 0.72 | SLC6A4 (0.34) | SLC6A4TAS1R3TAS1R1MAOANPC1 | |
| SCHEMBL17710305 | 0.72 | SLC6A4 (0.34) | SLC6A4TAS1R3TAS1R1MAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139595-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |