Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.42 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696384 | 0.86 | TACR1 (0.45) | TACR1TAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL20459563 | 0.83 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL22873009 | 0.83 | TACR1 (0.42) | TACR1KMT2AMEN1TAAR1MAN2A1 | |
| SCHEMBL22456931 | 0.81 | TACR1 (0.41) | TACR1KMT2AMEN1TAAR1MAN2A1 | |
| SCHEMBL9667082 | 0.80 | TACR1 (0.40) | TACR1KMT2AMEN1TAAR1EPHX1 | |
| SCHEMBL5223140 | 0.79 | MEN1 (0.47) | TACR1TAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL13317650 | 0.79 | MEN1 (0.47) | TACR1TAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL24304092 | 0.79 | TACR1 (0.51) | TACR1KMT2AMEN1TAAR1MAN2A1 | |
| SCHEMBL11211111 | 0.78 | EPHX1 (0.44) | TACR1KMT2AMEN1TAAR1EPHX1 | |
| SCHEMBL23642178 | 0.78 | SLC6A4 (0.37) | TACR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292589-A1 | Novel multifunctional peptidase inhibitors, especially for medical use | IMTM GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |