SCHEMBL2364438

SCHEMBL2364438

COC(C)c1nc2c(c(C3CCN(C(=O)OCc4ccccc4)CC3)c1C(=O)c1ccc(C(F)(F)F)cc1)C(O[Si](C)(C)C(C)(C)C)CC(C)(C)C2

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL969737 1.00 CETP (0.61) CETP
SCHEMBL972496 0.89 CETP (0.51) CETP
SCHEMBL970879 0.89 CETP (0.77) CETP
SCHEMBL12921451 0.86 CETP (0.62) CETP
SCHEMBL972847 0.85 CETP (0.54) CETP
SCHEMBL973056 0.84 CETP (0.60) CETP
SCHEMBL2363979 0.80 CETP (0.56) CETP
SCHEMBL972937 0.80 CETP (0.56) CETP
SCHEMBL2361061 0.80 CETP (0.53) CETP
SCHEMBL974455 0.80 CETP (0.53) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268644-B1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INT (DE) 2011-08-17 EP disclosed