Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.69 |
| ▸ | PPARA | Q07869 | 14/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669667 | 0.95 | PPARG (0.65) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL295888 | 0.89 | SMN1; SMN2 (0.64) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4651839 | 0.89 | SMN1; SMN2 (0.64) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4820511 | 0.88 | SMN1; SMN2 (0.59) | PPARGPPARACYP1A2GAACYP2C9 | |
| Hydrochloric Acid SCHEMBL11617632 | 0.87 | SMN1; SMN2 (0.62) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4818098 | 0.87 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL1564972 | 0.84 | PPARG (0.61) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL420670 | 0.84 | SMN1; SMN2 (0.63) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4818478 | 0.84 | PPARG (0.58) | PPARGPPARAGAASMN1; SMN2 | |
| SCHEMBL11550284 | 0.84 | SMN1; SMN2 (0.67) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2355826-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | The Cleveland Clinic Foundation (US) | 2011-08-17 | — | — | EP | disclosed |