Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | PPARA | Q07869 | 16/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382021 | 0.86 | SMN1; SMN2 (0.59) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4815612 | 0.85 | SMN1; SMN2 (0.60) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4814698 | 0.85 | SMN1; SMN2 (0.57) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL2364446 | 0.84 | PPARG (0.69) | PPARGPPARASMN1; SMN2GAA | |
| SCHEMBL5727504 | 0.83 | SMN1; SMN2 (0.56) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4820511 | 0.83 | SMN1; SMN2 (0.59) | PPARGPPARASMN1; SMN2GAA | |
| SCHEMBL28669667 | 0.82 | PPARG (0.65) | PPARGPPARASMN1; SMN2GAA | |
| SCHEMBL11046248 | 0.82 | TP53 (0.60) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL4818098 | 0.81 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL4277047 | 0.81 | SMN1; SMN2 (0.54) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | PPARG 570/4885PPARA 752/4885SMN1; SMN2 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.