Sialic Acid

Sialic Acid

SCHEMBL236448

CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)OC(O)(C(=O)O)C[C@@H]1O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.72
L3MBTL1 Q9Y468 1/20 0.68
NEU2 Q9Y3R4 3/20 0.47
NEU4 Q8WWR8 2/20 0.47
NEU3 Q9UQ49 2/20 0.47
NEU1 Q99519 1/20 0.47
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
MAG P20916 2/20 0.42
SIGLEC7 Q9Y286 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sialic Acid SCHEMBL22412 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL12391269 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL22879166 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL20299824 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL23366253 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL804644 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL24274184 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL22279106 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL21067569 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3
Sialic Acid SCHEMBL22943658 1.00 NANP (0.72) NANPL3MBTL1NEU2NEU4NEU3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4785 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747629-A2 APOPTOSIS DETECTION Loughborough University (GB) 2026-05-27 EP claimed
EP-4747630-A1 USE OF THE GLYCANS AS SENESCENT CELL SURFACE MARKERS Loughborough University (GB) 2026-05-27 EP claimed
EP-4742899-A1 METHOD TO IMPROVE A PLANT'S GROWTH, DEVELOPMENT AND RESISTANCE TO (A)BIOTIC STRESS Globachem NV (BE) 2026-05-20 EP claimed
US-20260132407-A1 VIVO SYNTHESIS OF SIALYLATED COMPOUNDS INBIOSE N V (BE) 2026-05-14 US claimed
EP-4728277-A1 NEAR REAL TIME SIALIC ACID QUANTITATION OF GLYCOPROTEINS Bristol-Myers Squibb Company (US) 2026-04-22 EP claimed
US-12582612-B2 Pharmaceutical composition of Siglec-binding agents CYTODIGM, INC. (US) 2026-03-24 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-3270714-B1 COMPOSTION COMPRISING SIALLYLLACTOSE FOR USE IN ENHANCING LEARNING SKILLS AND MEMORY FUNCTION NESTLE SA (CH) 2026-03-11 EP claimed
EP-4704597-A1 METHOD TO REDUCE FEED CONVERSION RATIO IN A FARMED ANIMAL Inbiose N.V. (BE) 2026-03-11 EP claimed
EP-4702138-A1 PRODUCTION OF A NEGATIVELY CHARGED OLIGOSACCHARIDE BY A CELL Inbiose N.V. (BE) 2026-03-04 EP claimed
CN-101165190-B Preparation for N-acetylneuraminic acid by immobilization double-enzyme method SHANGHAI INST BIOL SCIENCES 2011-08-24 CN claimed
US-20100273207-A1 Methods for Diagnosis of Sepsis and Risk of Death LANGLEY RAYMOND 2010-10-28 US claimed
WO-2010124269-A1 METHODS FOR DIAGNOSIS OF SEPSIS AND RISK OF DEATH NATIONAL CENTER FOR GENOME RESOURCES (US) 2010-10-28 WO claimed
US-7749700-B2 Differential expression of molecules associated with acute stroke THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2010-07-06 US claimed
CN-101165190-A Preparation for N-acetylneuraminic acid by immobilization double-enzyme method CHINESE ACADEMY OF SCIENCES SH (CN) 2008-04-23 CN claimed
CN-1227495-A Compositions of plant carbohydrates as dietary supplements MANNATECH INC (US) 1999-09-01 CN claimed
EP-0386721-B1 Sodium N-acetylneuraminate trihydrate and method for the preparation thereof KANTO ISHI PHARMA CO LTD (JP) 1995-02-08 EP claimed
EP-0164754-B1 PROCESS FOR PRODUCING N-ACETYLNEURAMINATE LYASE KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-03-06 EP claimed
US-4670389-A FROM ESCHERICHIA KYOWA HAKKO KOGYO CO., LTD. (JP) 1987-06-02 US claimed
EP-0164754-A1 Process for producing N-acetylneuraminate lyase KYOWA HAKKO KOGYO CO., LTD. (JP) 1985-12-18 EP claimed