Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 11/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.57 |
| ▸ | PSMB9 | P28065 | 8/20 | 0.57 |
| ▸ | PSMB6 | P28072 | 8/20 | 0.57 |
| ▸ | PSMB10 | P40306 | 8/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 7/20 | 0.57 |
| ▸ | PSMA7 | O14818 | 7/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.57 |
| ▸ | PSMA1 | P25786 | 7/20 | 0.57 |
| ▸ | PSMA2 | P25787 | 7/20 | 0.57 |
| ▸ | PSMA3 | P25788 | 7/20 | 0.57 |
| ▸ | PSMA4 | P25789 | 7/20 | 0.57 |
| ▸ | PSMA5 | P28066 | 7/20 | 0.57 |
| ▸ | PSMB4 | P28070 | 7/20 | 0.57 |
| ▸ | PSMB3 | P49720 | 7/20 | 0.57 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.57 |
| ▸ | PSMA6 | P60900 | 7/20 | 0.57 |
| ▸ | PSMA8 | Q8TAA3 | 7/20 | 0.57 |
| ▸ | PSMB7 | Q99436 | 7/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30529994 | 0.89 | PSMB5 (0.71) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL10005021 | 0.89 | PSMB5 (0.71) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL10004622 | 0.88 | PSMB5 (0.58) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL21977971 | 0.88 | PSMB5 (0.58) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL10005139 | 0.87 | PSMB5 (0.59) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL10004915 | 0.86 | PSMB5 (0.55) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL17667669 | 0.85 | PSMB5 (0.53) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL21841192 | 0.84 | PSMB5 (0.80) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL23645176 | 0.83 | PSMB5 (0.57) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL30529995 | 0.83 | PSMB5 (0.57) | PSMB5PSMB8PSMB9PSMB6PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12157749-B2 | Borate-based drug and use thereof | CHENGDU ORIGIN BIOTECHNOLOGY LIMITED COMPANY (CN) | 2024-12-03 | — | — | US | disclosed |
| EP-3851108-B1 | BORATE-BASED DRUG AND USE THEREOF | CHENGDU ORIGIN BIOTECHNOLOGY LTD COMPANY (CN) | 2023-08-09 | — | — | EP | disclosed |
| US-20210332069-A1 | Borate-Based Drug And Use Thereof | CHENGDU ORIGIN BIOTECHNOLOGY LIMITED COMPANY (CN) | 2021-10-28 | — | — | US | disclosed |
| EP-3851108-A1 | BORATE-BASED DRUG AND USE THEREOF | Chengdu Origin Biotechnology Limited Company (CN) | 2021-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332069-A1 | Borate-Based Drug And Use Thereof | PSMB11, PSMB1, PSMB3 | PSMB5 8/4885PSMB8 11/4885PSMB9 18/4885 |
| US-12157749-B2 | Borate-based drug and use thereof | PSMB11, PSMB1, PSMB3 | PSMB5 8/4885PSMB8 11/4885PSMB9 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.